AdiPress uses proprietary technology (Automated Compressive Filtration, or ACF) to physically separate adipose fat from lymph nodes. The result of ACF is a defatted tissue specimen containing lymph nodes and surrounding vasculature / connective tissue. This concentrated lymphatic tissue is captured in square wells in the specialized LymFilte containers that are perfectly sized for paraffin-embedding in standard cassettes. that can then be prepared for standard microscopic analysis.
AdiPress reduces the mass of the sample by up to 5x (i.e. 20% of the original mass) This filtration action removes adipose fat while preserving lymph nodes and surrounding connective tissue and vasculature. The filtered tissue is submitted in entirety. AdiPress does not identify individual lymph nodes via compressive filtration.
AdiPress is calibrated to preserve lymph node morphology while efficiently compressing the sample. Labs report clear morphology and slides that are easy to read due to the lack of adipose fat obscuring the lymph nodes. Photo examples are available on request - please reach out to sales@formapath.com for more information.
The dimensions of AdiPress are 20in (H) x 12in (W) x 12in (D) [500mm (H) x 300mm (W) x 300mm (D)]. The device can easily sit on the existing lab bench.
Manual grossing for lymph nodes is the process of identifying individual lymph nodes through manual palpation, visual observation, and using hand tools such as forceps and scalpels. This approach is time-consuming and dependent on the skill and training of the Grosser.
Using the AdiPress enables the Grosser to quickly shrink the tissue specimen to a manageab size while maintaining a reasonable number of glass slides. Because all lymph nodes contained within the tissue sample are submitted and processed, this allows for Census-Level Nodal Assessment, resulting in higher overall identification rates.
Due to the sample being defatted, labs report efficient processing and staining. Pathologists report clean histology making lymph node identification and interpretation efficient. Photo examples are available on request - please reach out to sales@formapath.com for more information.
Any tissue where adipose fat is obscuring the identification of lymph nodes. Colon and rectum cases are great candidates for AdiPress due to the heightened significance of analyzing lymph nodes and the significant adipose fat that these specimens often contain.
We’d love to discuss your lab’s needs for AdiPress! Please reach out to sales@formapath.com to get in contact with one of our team members directly to schedule a demo and discuss lease terms.
AdiPress uses LymFilters and acetone to process each case. A starter pack of LymFilters and acetone will be included with initial delivery of AdiPress. Additional LymFilters can be purchased for a nominal cost.
LymFilters are validated to work with routine formalin fixed samples that undergo a secondary fixation in acetone.
FormaPath’s expert technicians will conduct on-site, in-person training during the installation visit.
Whomever was previously manually dissecting tissue specimens can continue to be in charge of this part of the process. AdiPress is designed to be easy to use for lab staff of all experience levels. For more detailed examples of how labs are currently using the AdiPress, please reach out to sales@formapath.com.
Every leased device is bundled with an annual service plan. We will respond to service requests within 24 hrs (although likely much faster) and will fix or replace any defect that arises through normal use.